Syllabus
| WEEK | DATE | LECTURE | READING |
|---|---|---|---|
| 1 | 8-28 8-30 |
Introduction to Immunology Cells of the immune system and lymphoid organs |
Ch. 1 Ch. 2 |
| 2 | 9-4 9-6 |
Innate immunity I Innate immunity II |
Ch. 3 |
| 3 | 9-11 9-13 |
Complement system / HW1 DUE Adaptive Immunity |
Ch. 7 Ch. 8 |
| 4 | 9-18 9-20 |
MHC restriction and thymic selection Dendritic cells |
Ch. 8 Heesters et al., 2014 |
| 5 | 9-25 9-27 |
Antigen processing and presentation Immunoglobulin rearrangement / HW2 DUE |
Ch. 6 and Kloetzel 2001 Ch. 5 |
| 6 | 10-2 10-4 |
T cell differentiation and response B cell activation and humoral immunity |
Ch. 10 Ch. 11 |
| 7 | 10-9 10-11 |
ESSAY 1 Tolerance and autoimmunity |
Ch. 16 and Onishi et al. 2008 |
| FALL | BREAK | ||
| 8 | 10-23 10-25 |
Applications Lab Lecture |
Ch. 22 Boyman and Sprent 2012 |
| 9 | 10-30 11-1 |
LAB I: IL-2 in splenocytes Tumor immunology (freeze IL-2 samples) |
Ch. 21 |
| 10 | 11-6 11-8 |
Transplantation LAB II: ELISA to detect IL-2 |
Ch. 17 |
| 11 | 11-13 11-15 |
Mucosal immunity / HW3 DUE Immunity to viruses |
Turner et al. 2009 Ch. 18 |
| 12 | 11-20 11-22 |
HIV targets CD4 T cells THANKSGIVING |
Ch. 20 and Doitsh et al. 2014 |
| 13 | 11-27 11-29 |
Vaccinology / LAB REPORTS DUE Tim Nice, Ph.D. |
Ch. 19 Nice et al. 2018 |
| 12-4 | Primary research article – class choice | Warfel et al. 2016 | |
| 12-13 | FINAL ESSAY EXAM DUE |